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- md.ibrahim@cnsu.edu
- Lab Location, 9700 W Taron Dr, Elk Grove, CA 95757
We study how disruption of the NAD⁺–PARP1–XRCC1 axis contributes to persistent DNA damage and metabolic stress in ALS. Therapeutic approaches include PARP inhibitors, NAD-boosting agents, and mRNA-LNP delivery to neurons and glia. Our aim is to protect against neuronal death and slow disease progression.