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I B R A H I M R S E A R C H

My lab investigates DNA damage repair and replication stress pathways that drive resistance to chemotherapy and PARP inhibitors. We develop siRNA-loaded lipid nanoparticles to silence undruggable repair and checkpoint proteins in glioblastoma, ovarian, and breast cancers. The goal is to restore sensitivity to temozolomide, PARP inhibitors, and other alkylating agents.

Precision Discovery. On Track to Cure.